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The workshop was introductory, aimed at thesis
students/postdocs/staff with some familiarity with DNA sequence
data, but who wanted to increase their awareness of issues
in and methods of comparative evolutionary analysis. The workshop
included an introduction to different comparative approaches
(distance, parsimony, ML) their philosophy, assumptions, and
parameters (GC content, among-site rate heterogeneity, tv:ti,
syn:nonsyn, weighting, statistical support) and some general
relevant thoughts about molecular evolution (saturation, orthology,
coalescence, lineage sorting).
After the tea-break, Marty Kennedy demonstrated
the implementation of these algorithms in a single comprehensive
soon-to-be-released beta version of the package PAUP*4.0 (Phylogenetic
Analysis Using Parsimony) written by Dave Swofford at the
Smithsonian. Graham also distributed a short list of review-style
references in the area and information on purchasing PAUP.
The workshop was supported by the Research
Theme: Gene Structure & Function and the CGR. Enrolment was
restricted to 24 participants and it was fully booked.
Graham Wallis
Senior Lecturer in Genetics
Department of Zoology
(Associate Editor, Molecular Ecology)
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